Genome accessibility reveals disease risk that gene expression misses
The effects of disease-associated genetic variants on gene expression and genome accessibility have been analysed together. The work is summarized from Kanai, M. et al., “Population-scale immune multiome atlas reveals regulatory disease mechanisms,” published in Nature in 2026.
Analysing gene expression and genome accessibility together gives researchers a broader view of how disease-associated genetic variants affect the genome.
Written by the Genomes desk from the primary source cited and linked above and checked against it. Research use only; not medical advice. Corrections: [email protected].